The office is chaired by the Vice President for Academic Affairs. It supervises the following faculties:

1. Faculty of Technology and Applied sciences.
2. Faculty of Agriculture.
3. Faculty of Social and Family Development.
4. Faculty of Administrative and Economic Sciences.
5. Faculty of Educational Sciences.
6. Faculty of Media.
7. Faculty of Arts.
8. Faculty of Graduate Studies.

In addition to the supervision of other deanships, departments and centers:

• Deanship of Scientific Research.
• Deanship of Graduate Studies.
• Deanship of Admission, Registration and Examination.
• Deanship of Curriculum and Textbooks.
• Department of Libraries.
• Assessment Center.
• Open Learning Center(OLC).
• Continuing Education Center and Community Service (CEC).
• Future Studies and Opinion Polls Center.
• Media Production Center (MPC).
• Information Technology and communications Center (ICTC).

The Vice President for Administrative Affairs Office is responsible for drafting, revising, developing, and updating regulations and bylaws of the University to best serve QOU and its staff. The office supervises the execution and implementation of the bylaws and regulations in all of its administrative units, in a precise and professional manner.

Other missions include addressing the requirements of the various administrative units at the University through the recruitment of qualified and competent staff, supplement of equipment and tools, and providing any other needed administrative services or tasks. The office also fosters and boosts the development and operations of the Academic Affairs' Office. Furthermore, it follows up the legal affairs of the University with the legal advisors.

The Administrative Affairs Office is also concerned with the implementing of sound performance of its units through two steps, Comprehensive monitoring and supervision of its procedures; and the follow up with the latest updates and technology

In addition to the aforementioned, the office supervises the following:

1. Human Resources Department,
2. Procurement & Supplies Department
3. Planning & Quality Department
4. Engineering & Construction Unit
5. Central Bureau (Central Archive Office)
6. Services & Maintenance
7. Mail and Mobility section

Besides following up legal issues with legal consultants of the University